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What is Natural Modified IVF

Natural Modified IVF (also known as Natural Cycle Modified IVF) involves egg collection within a woman’s menstrual cycle. Like Natural Cycle IVF, the focus is on collecting one high quality egg that has been naturally selected by the body, although sometimes more than one egg can be collected.

Natural Modified IVF differs to Natural IVF as during this process, medication is given for 3-4 days in order to block spontaneous ovulation (prior to egg collection), and a small dose of stimulation hormone is given to keep the follicles healthy and growing. For women who want to avoid injections, we can tailor the Natural Modified IVF cycle using tablets.

Who is it for?

  • Those with a low egg reserve whose blood tests have indicated that they have low levels of Anti-Müllerian Hormone (AMH) or high levels of Follicle Stimulating Hormone (FSH)
  • Those with low antral follicle count in their ovaries
  • Couples/women who have had previous failure of implantation with conventional IVF
  • Women who have produced fewer than three eggs with conventional IVF (poor responders)
  • Those that want to reduce the physical and psychological burden associated with conventional IVF

Your guide to fertility treatments and services

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What are the benefits of Natural Modified IVF?

 Higher egg and embryo quality
Higher egg and embryo quality
 Higher egg and embryo quality
Higher egg and embryo quality

Egg and embryo quality are considered to be better in Natural Modified IVF compared with conventional IVF.

Better for implantation
Better for implantation
Better for implantation
Better for implantation

The lining of the womb is more favourable for implantation in Natural Modified IVF.

Fewer side effects and risks
Fewer side effects and risks
Fewer side effects and risks
Fewer side effects and risks

As with all our approaches, Natural Modified IVF offers a less invasive approach and the use of lower doses of fertility drugs leads to fewer potential risks and side effects.

 Excellent success rates
Excellent success rates
 Excellent success rates
Excellent success rates

We are especially proud of our success rates with very low egg reserve, those in older age groups, and poor responders to stimulation drugs

Reduced cost
Reduced cost
Reduced cost
Reduced cost

Natural Modified IVF is more affordable per cycle than conventional IVF treatments as it does not require as many costly drugs.


Your IVF treatment journey at CREATE

Previous step
Step 1:
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Next step
  • Initial Consultation & Scan

    The first step is for you to come in for an Initial Consultation & scan where one of our IVF Consultants will assess you and devise a personalised treatment plan which will give you the best chance of success.

  • Treatment Consultation

    2 weeks before the start of your period you will come in to meet with a fertility nurse who will talk you through your treatment plan and go through the consent forms with you.


  • Scans & Blood tests

    You will have 2 or 3 monitoring scans usually spaced days apart; each takes 20 minutes. The doctor may perform blood tests at these appointments.


  • Egg collection

    This procedure is performed in the theatre under sedation and takes around 45 minutes.


  • Embryo Transfer

    The embryo transfer is a quick and easy procedure which does not need sedation and feels similar to a smear test

  • Pregnancy test

    We will invite you back to the clinic for a pregnancy blood test and give you the test results by the end of the day.

    Start your journey


Natural Modified IVF success rates

We are especially proud of our success rates with women with low egg reserve, those in older age groups and those who do not respond well to stimulation drugs.

Natural Cycle IVF success rates

Clinical pregnancies per treatment cycle | Natural Cycle IVF | July 15 - June 16 | CREATE St Paul's

Benefits of the 3 cycle package

With our 3-cycle Natural Modified IVF treatment, we provide you with 3 cycles of Natural Modified IVF. We freeze the embryos that result from the 3 cycles and then transfer the best embryo(s) in a Frozen Embryo Transfer Cycle(s).

1. Greatly improved success rates
Greatly improved success rates compared to a single cycle.
Cost saving
2. Cost saving
A ‘3 Cycle Package’ is more affordable than doing 3 separate cycles. This also means that for any spare embryos, you’ll only need to have a Frozen Embryo Transfer (FET) in the future.
3. Time reduction
In circumstances where egg reserve is low/critical and time is of the essence, the package allows for multiple embryo creation over a short period of time for future use.
4. Future use
Any spare embryos can be frozen and implanted at a later stage.

0% interest payment plans available

Spread the cost of your treatment

We want to make growing your family less stressful and more manageable by making sure your focus is on getting pregnant and having a baby. That's why we've introduced new cost-effective payment plans for our patients to help you make your family dreams a reality.


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Our thoughts on Natural IVF

Read the latest stories, advice and news from the CREATE Fertility blog.