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Natural Modified IVF

Natural Modified IVF (also known as Natural Cycle Modified IVF) is a form of Natural Cycle IVF. The treatment is carried out within your natural menstrual cycle – like Natural IVF – but is modified by introducing additional medication. Natural Modified IVF has an improved success rate compared with Natural IVF while retaining many of the benefits.

We are especially proud of our success rates for women with low egg reserve and those in older age groups using Natural Modified IVF.

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If you have a question about Natural Modified IVF or choosing the best treatment option for you then you can contact our experienced team who will be happy to help.

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What is Natural Modified IVF?

Natural Modified IVF involves egg collection within a woman’s menstrual cycle. Like Natural Cycle IVF, the focus is on collecting one high quality egg that has been naturally selected by the body, although sometimes more than one egg can be collected.

Natural Modified IVF differs to Natural IVF as during this process, medication is given for 3-4 days in order to block spontaneous ovulation (prior to egg collection), and a small dose of stimulation hormone is given to keep the follicles healthy and growing. For women who want to avoid injections, we can tailor the Natural Modified IVF cycle using tablets.

Embryo cell

Advantages of Natural Modified IVF

Quality over quantity
Quality over quantity

Egg and embryo quality are considered to be better in Natural Modified IVF compared with conventional IVF.

Better for implantation
Better for implantation
Better for implantation

The lining of the womb is more favourable for implantation in Natural Modified IVF.

Fewer side effects
Fewer side effects

As with all our approaches, Natural Modified IVF offers a less invasive approach and the use of lower doses of fertility drugs leads to fewer potential risks and side effects.

Safer for women
Safer for women

The risk of Ovarian Hyperstimulation Syndrome (OHSS) is reduced with Natural Modified IVF and there are no menopausal side-effects.

Excellent success rates
Excellent success rates
Excellent success rates

We are especially proud of our success rates with very low egg reserve, those in older age groups, and poor responders to stimulation drugs

Reduced cost
Reduced cost
Reduced cost

Natural Modified IVF is more affordable per cycle than conventional IVF treatments as it does not require as many costly drugs.

No breaks needed
No breaks needed

Patients who choose this option can repeat their treatment in consecutive natural cycles, rather than taking a break of a few months between treatments.

Our success rates

We are especially proud of our success rates with women with low egg reserve, those in older age groups and those who do not respond well to stimulation drugs.

View our success rates

Natural Cycle IVF Success Rates Graph

Clinical pregnancies per treatment cycle | Natural Cycle IVF | July 15 - June 16 | CREATE St Paul's


Who is Natural Modified IVF suitable for?

All women who ovulate are suitable for Modified Natural IVF treatment. In particular:

  • Patients with low egg reserve whose blood tests have indicated that they have low levels of Anti-Müllerian Hormone (AMH) or high levels of Follicle Stimulating Hormone (FSH)
  • Patients with low antral follicle count in their ovaries
  • Couples/women who have had previous failure of implantation with conventional IVF
  • Women who have produced fewer than three eggs with conventional IVF (poor responders)
  • Those who want to reduce the risks and side effects associated with conventional IVF.

Want more information about Natural Modified IVF
at CREATE Fertility

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The Natural Modified IVF process

Initial scan and consultation
Initial Consultation & Scan

The first step is for you to come in for an Initial Consultation & scan where one of our IVF Consultants will assess you and devise a personalised treatment plan which will give you the best chance of success.

Treatment Consultation

2 weeks before the start of your period you will come in to meet with a fertility nurse who will talk you through your treatment plan and go through the consent forms with you.

Scans & Blood tests

You will have 2 or 3 monitoring scans usually spaced days apart; each takes 20 minutes. The doctor may perform blood tests at these appointments.

Egg collection

This procedure is performed in the theatre under sedation and takes around 45 minutes.

Embryo Transfer

The embryo transfer is a quick and easy procedure which does not need sedation and feels similar to a smear test

Pregnancy test

We will invite you back to the clinic for a pregnancy blood test and give you the test results by the end of the day.

Have a question about Natural Modified IVF?

Get in touch with us to discuss any further questions or to book an appointment.

Contact us

To request more information

Speak to our experienced team
0333 240 7300

Lines open 8am - 6pm Monday to Friday.

Attend a free open evening

With one of our fertility experts