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What is PGT-M?

PGT-M is a technique used to assess embryos for genetic diseases and chromosomal abnormalities. It involves the removal of one or more cells from embryos before they are transferred. The cells are then screened for any genetic disease that is known to be carried in the family.

PGT-M can be used to look for single-gene disorders (inherited diseases caused by a single faulty gene) and chromosomal translocations. Unaffected embryos can then be selected for re-implantation. This protects resulting children from inheriting the disease. 

Who is it suitable for?

PGT-M is primarily used for individuals/couples who are known carriers or suffers of inherited disease. There are over 4000 conditions caused by single-gene mutations which can be tested for using PGD. Some of the most common are Huntington’s disease, cystic fibrosis and sickle-cell anaemia.

PGD
 

Advantages of PGT-M

Improves IVF success rates
Improves IVF success rates
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Improves IVF success rates
Improves IVF success rates

Genetically healthy embryos are more likely to implant and result in birth.

It reduces the risk of passing on inherited disease
It reduces the risk of passing on inherited disease
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It reduces the risk of passing on inherited disease
It reduces the risk of passing on inherited disease

PGD allows individuals/couples with known inherited disease to have a child who is likely to be free from disease.

It can be used to diagnose Down Syndrome
It can be used to diagnose Down Syndrome
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It can be used to diagnose Down Syndrome
It can be used to diagnose Down Syndrome

In PGS the number of chromosomes is examined and likely cases of Down Syndrome can be identified.

 

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