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Natural Cycle IVF with IVM

In Vitro Maturation (IVM) is a revolutionary IVF treatment, which has been pioneered by our Scientific Director, Professor R C Chian. It involves the collection of immature eggs, which are then matured in the laboratory.

By this method, it is possible to collect multiple eggs without giving hormone stimulation. We were the first IVF clinic in Europe to offer Natural Cycle IVF treatment with IVM.

Who is it for?

This treatment can be used for anyone who is ovulating and who is recommended to do IVM by one of our doctors. It can be particularly useful for people for whom time is short, or who are unable to take fertility medication (due to an oestrogen dependent tumour for example).

Natural Cycle IVF with IVM is also a successful alternative for women with Polycystic Ovaries (PCO) or Polycystic Ovarian Syndrome (PCOS).

What is IVM?

During each menstrual cycle, usually only a single follicle (egg sac) grows to the ovulation stage to release an egg for potential fertilisation. However, there are several small follicles called antral follicles in the ovary which contain immature eggs. With IVM these can be collected and matured in the laboratory using special and advanced culture conditions to create several embryos.

Advantages of IVM Treatment

More embryos
More embryos
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More embryos
More embryos

Around 70-80% of immature eggs collected from the ovaries will mature 24-48 hours after culture in the laboratory.

Safer for women
Safer for women
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Safer for women
Safer for women

Natural Cycle IVF with IVM avoids the effects of stimulation drugs and eliminates the risk of Ovarian Hyperstimulation Syndrome (OHSS).

 Increased success rate
Increased success rate
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 Increased success rate
Increased success rate

Creating more embryos can lead to an increased chance of pregnancy.

Healthy babies
Healthy babies
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Healthy babies
Healthy babies

So far, there have been more than 2500 healthy babies born worldwide following the collection of immature eggs which were matured with IVM.

 Better for implantation
Better for implantation
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 Better for implantation
Better for implantation

By avoiding stimulating drugs, the womb is more receptive to pregnancy.

More affordable
More affordable
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More affordable
More affordable

Natural IVF is less expensive per cycle than Stimulated IVF treatments as it does not require costly medication.

 Consultant led care
Consultant led care
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 Consultant led care
Consultant led care

Your treatment will be led throughout by our doctors, which differs from other clinics, where care is often led by the nursing team.

CREATE gave us hope!

CREATE’s approach did not focus on numbers, they really looked after me; an approach which has proven to work!